Analytical Chemistry

Discovery - Chemistry

 

A full suite of analytical services and quality control supports disciplines within our integrated drug discovery environment. Capabilities such as high throughput LC-MS analysis, HR-LCMS determination of minor components, 600 MHz NMR, GC-MS, and LC-MS analysis of biological samples are all part of our repertoire of analytical support.

In addition, our Analytical group provides expertise in the following areas:

  • Assessment of chemical stability in time course under prescribed conditions
  • Determination of kinetic solubility of compounds from 10 mM DMSO stock solution
  • Automated HPLC-based assessment of logD at three pH values
  • Metabolite (hot-spot) analysis by LC-MS-MS
  • Custom methods development
  • High throughput assessment of compound concentration