Multi-Parametric SAR Optimization
Discovery - Chemistry
Multi-Parametric SAR Optimization is central to Icagen’s early discovery efforts, enabling faster, more efficient progression toward Lead or Pre-Candidate status. The simultaneous optimization of physicochemical properties, such as potency, solubility, stability, and permeability, not only improves overall efficiency with regard to lead optimization, but also increases the candidate’s probability of success through preclinical and clinical trials.
Icagen’s lead discovery process and capabilities include:
Icagen’s compound optimization methodologies involve: