Integrated Drug Discovery

Discovery

Effective drug discovery campaigns are executed by interdisciplinary, tight-knit teams working in close communication, reviewing data in real time and continuously adjusting to events and conditions to overcome obstacles. At Icagen, drug discovery occurs in a web of biology, chemistry, structural biology and in silico modeling, in which reevaluations and readjustments happen seamlessly and in real time.

An Icagen scientist is a different kind of scientist, possessing not only specialized knowledge of a particular field, but a unique translational knowledge of all fields, demonstrating that true integration leads to the discovery of strong drug candidates. This is how Icagen chemists, biologists and computational scientists have worked together for nearly two decades.

Our integrated approach combines the experience of our scientists, the agility of our teams, and the transparency of our communications to provide a turnkey solution for your most challenging programs. An Icagen partner will find everything they need under one roof.

Our Integrated Drug Discovery capabilities include:

  • Early Discovery
    • Target Biology
    • Cell Line Development
    • Assay Development
    • Computational Druggability Assessment
  • Hit Identification
    • Assay Development
    • High Throughput Screening
    • Secondary Screening
    • Orthogonal Screening
    • Profiling
    • Medicinal Chemistry
    • In vitro early ADME
    • Synthetic chemistry
  • Hit to Lead
    • MOA
    • Potency/Selectivity
    • In vitro safety
  • Lead Optimization
    • Potency/selectivity optimization
    • Safety