Molecular Biology & Biomarkers
Tools & Technologies - Biology
The ability to understand the transcriptional and translational effects of drug candidates is transformative in the discovery process, often enabling assay read-outs closer to desired cellular endpoints. This can be especially powerful when combined with primary cells, or iPSC derived cells in patho-physiologically relevant models. Biomarker identification and detection obviates the need to construct artificial “reporter” systems, saving time and money and avoiding their commonly associated artefacts.
The choices of diseased state “signatures,” be it with respect to transcriptional response patterns or post-translational modifications, are critical for success. Icagen is prepared to help you identify and select the biomarkers most relevant to the processes you wish to modulate.