Binding Site Analysis

Tools & Technologies - in silico Drug Discovery

Computational analysis of binding sites of biomolecules is critical in understanding their potential druggability. It is also important in addressing possible selectivity and poly-pharmacology effects of ligands. We routinely use both publicly available and proprietary in-house tools for binding site analysis and the study of allosteric pockets. Our team has a strong track record of exploiting these tools to design selective compounds based on such analysis and elucidation of cryptic pockets of flexible macromolecules. With over a decade of experience using such approaches, our team understands both the power and limits of these methods and can provide valuable insight on their potential as an integral part of your discovery plan.